Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 5/20 | 0.48 |
| ▸ | PLAU | P00749 | 5/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771732 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2USP2HTTPLGPLAU | |
| SCHEMBL6771728 | 0.99 | SMN1; SMN2 (0.52) | SMN1; SMN2USP2HTTPLGPLAU | |
| Hydroxyamine SCHEMBL7552923 | 0.98 | SMN1; SMN2 (0.52) | SMN1; SMN2USP2HTTPLGPLAU | |
| SCHEMBL6768081 | 0.97 | SMN1; SMN2 (0.52) | SMN1; SMN2USP2HTTPLGPLAU | |
| SCHEMBL6777349 | 0.90 | MMP1 (0.51) | SMN1; SMN2USP2HTTMMP1MMP13 | |
| SCHEMBL6767794 | 0.90 | MMP1 (0.51) | SMN1; SMN2USP2HTTMMP1MMP13 | |
| SCHEMBL6771228 | 0.89 | MMP1 (0.50) | MMP1MMP13ADAM17 | |
| SCHEMBL6778949 | 0.88 | MMP1 (0.49) | MMP1MMP13ADAM17 | |
| SCHEMBL6772598 | 0.83 | HTT (0.55) | SMN1; SMN2USP2HTTPLGPLAU | |
| Hydroxyamine SCHEMBL7578513 | 0.81 | HTT (0.53) | SMN1; SMN2USP2HTTPLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6677355-B1 | DIBENZOFURAN-3-(SULFONYLAMINO OR SULFINAMINO) DERIVATIVES; MULTIPLE SCLEROSIS, ATHEROSCLEROSIS, HEART FAILURE, PERIODONTAL DISEASE, OSTEOARTHRITIS, AUTOIMMUNE DISEASE; ANTICARCINOGENIC AGENTS | WARNER-LAMBERT COMPANY | 2004-01-13 | — | — | US | disclosed |