Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 6/20 | 0.49 |
| ▸ | PLG | P00747 | 5/20 | 0.49 |
| ▸ | PLAT | P00750 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770822 | 0.98 | SMN1; SMN2 (0.54) | SMN1; SMN2USP2HTTPLAUPLG | |
| SCHEMBL6771732 | 0.98 | SMN1; SMN2 (0.54) | SMN1; SMN2USP2HTTPLAUPLG | |
| SCHEMBL6771728 | 0.97 | SMN1; SMN2 (0.52) | SMN1; SMN2USP2HTTPLAUPLG | |
| SCHEMBL6768081 | 0.94 | SMN1; SMN2 (0.52) | SMN1; SMN2USP2HTTPLAUPLG | |
| SCHEMBL6777349 | 0.88 | MMP1 (0.51) | SMN1; SMN2USP2HTTMMP1MMP13 | |
| SCHEMBL6767794 | 0.88 | MMP1 (0.51) | SMN1; SMN2USP2HTTMMP1MMP13 | |
| SCHEMBL6771228 | 0.87 | MMP1 (0.50) | MMP1MMP13 | |
| SCHEMBL6778949 | 0.86 | MMP1 (0.49) | MMP1MMP13 | |
| Hydroxyamine SCHEMBL7578513 | 0.83 | HTT (0.53) | SMN1; SMN2USP2HTTPLAUPLG | |
| SCHEMBL6772598 | 0.81 | HTT (0.55) | SMN1; SMN2USP2HTTPLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210326-A2 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012592-A2 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-02-22 | — | — | WO | disclosed |