Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.51 |
| ▸ | MMP13 | P45452 | 17/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767794 | 1.00 | MMP1 (0.51) | MMP1MMP13ADAM17USP2HTT | |
| SCHEMBL6771228 | 0.99 | MMP1 (0.50) | MMP1MMP13ADAM17MMP2MMP3 | |
| SCHEMBL6778949 | 0.98 | MMP1 (0.49) | MMP1MMP13ADAM17MMP2MMP3 | |
| SCHEMBL6770822 | 0.90 | SMN1; SMN2 (0.54) | MMP1MMP13ADAM17USP2HTT | |
| SCHEMBL6771732 | 0.90 | SMN1; SMN2 (0.54) | MMP1MMP13ADAM17USP2HTT | |
| SCHEMBL6771728 | 0.89 | SMN1; SMN2 (0.52) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| Hydroxyamine SCHEMBL7552923 | 0.88 | SMN1; SMN2 (0.52) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| SCHEMBL6768081 | 0.86 | SMN1; SMN2 (0.52) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| SCHEMBL6771108 | 0.84 | MMP1 (0.51) | MMP1MMP13ADAM17USP2HTT | |
| SCHEMBL6771478 | 0.78 | MMP1 (0.47) | MMP1MMP13ADAM17MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1210326-A2 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-06-05 | — | — | EP | claimed |
| WO-2001012592-A2 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-02-22 | — | — | WO | claimed |
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6677355-B1 | DIBENZOFURAN-3-(SULFONYLAMINO OR SULFINAMINO) DERIVATIVES; MULTIPLE SCLEROSIS, ATHEROSCLEROSIS, HEART FAILURE, PERIODONTAL DISEASE, OSTEOARTHRITIS, AUTOIMMUNE DISEASE; ANTICARCINOGENIC AGENTS | WARNER-LAMBERT COMPANY | 2004-01-13 | — | — | US | disclosed |