Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071121 | 0.84 | HSD11B1 (0.50) | KMT2ALMNAMAPK1HSD11B1KDM4E | |
| Bromide SCHEMBL3853747 | 0.83 | KMT2A (0.51) | KMT2ALMNAMAPK1HSD11B1OPRM1 | |
| SCHEMBL6535502 | 0.77 | KMT2A (0.56) | KMT2AMAPK1OPRM1OPRD1ALDH1A1 | |
| Bromide SCHEMBL23535416 | 0.77 | KMT2A (0.50) | KMT2ALMNAMAPK1OPRM1OPRD1 | |
| SCHEMBL6766613 | 0.77 | SLC9A1 (0.47) | KMT2AMAPT | |
| Alagebrium SCHEMBL1820212 | 0.77 | KMT2A (0.71) | KMT2ALMNAMAPK1OPRM1OPRD1 | |
| Alagebrium SCHEMBL1648822 | 0.76 | KMT2A (0.74) | KMT2ALMNAMAPK1L3MBTL1OPRM1 | |
| Alagebrium SCHEMBL225618 | 0.76 | KMT2A (0.69) | KMT2ALMNAMAPK1OPRM1OPRD1 | |
| SCHEMBL5399193 | 0.75 | LMNA (0.44) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3845110 | 0.75 | KMT2A (0.53) | KMT2AMAPK1OPRM1OPRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790859-B2 | THERAPY OR REDUCING PROGRESSION OF HYPERTENSION OR DAMAGE TO A TISSUE CAUSED BY CONTACT WITH ELEVATED LEVELS OF REDUCING SUGARS IN AN ANIMAL, COMPRISING ADMINISTERING TO THE ANIMAL AN EFFECTIVE AMOUNT OF THIAZOLIUM COMPOUNDS | ALTEON INCORPORATED | 2004-09-14 | — | — | US | claimed |