Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MYOF | Q9NZM1 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771963 | 0.91 | MAPT (0.46) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6772832 | 0.91 | TP53 (0.47) | HPGDMEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL6779395 | 0.91 | TLR7 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL6772805 | 0.90 | TRPV1 (0.44) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL6768615 | 0.89 | TLR7 (0.39) | HDAC3HDAC1MAPTNAMPT | |
| SCHEMBL6778818 | 0.89 | HDAC3 (0.47) | MEN1KMT2AHDAC3HDAC1MAPT | |
| SCHEMBL6774328 | 0.86 | BRD4 (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6774215 | 0.85 | TLR8 (0.54) | SMN1; SMN2RAB9AMEN1KMT2AHDAC3 | |
| SCHEMBL6779782 | 0.85 | QPCT (0.46) | SMN1; SMN2HPGDALDH1A1KMT2AMAPT | |
| SCHEMBL6096076 | 0.85 | TLR7 (0.45) | SMN1; SMN2RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |