Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778546 | 0.92 | ALDH1A1 (0.45) | TLR7TLR8TP53RXFP1HDAC3 | |
| SCHEMBL6772832 | 0.92 | TP53 (0.47) | TLR7TLR8TP53HDAC3HDAC1 | |
| SCHEMBL6772805 | 0.91 | TRPV1 (0.44) | TLR7TLR8MCHR1HDAC3HDAC1 | |
| SCHEMBL6779395 | 0.90 | TLR7 (0.46) | TLR7TLR8TP53HDAC3HDAC1 | |
| SCHEMBL6772889 | 0.89 | SMN1; SMN2 (0.48) | HDAC3HDAC1MAPTNAMPT | |
| SCHEMBL6778818 | 0.87 | HDAC3 (0.47) | TLR7TLR8TP53HDAC3HDAC1 | |
| SCHEMBL6774328 | 0.85 | BRD4 (0.41) | TLR7TLR8TP53MAPT | |
| SCHEMBL6774215 | 0.84 | TLR8 (0.54) | TLR7TLR8TP53HDAC3HDAC1 | |
| SCHEMBL6779376 | 0.84 | HTR7 (0.38) | TLR7MAPT | |
| SCHEMBL6096076 | 0.84 | TLR7 (0.45) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |