Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772832 | 0.87 | TP53 (0.47) | BRD4TLR7TLR8DRD2DRD4 | |
| SCHEMBL6779395 | 0.87 | TLR7 (0.46) | TLR7TLR8DRD2DRD4DRD3 | |
| SCHEMBL6774215 | 0.86 | TLR8 (0.54) | BRD4TLR7TLR8DRD3TP53 | |
| SCHEMBL6772889 | 0.86 | SMN1; SMN2 (0.48) | DRD4DRD3MEN1KMT2ANPC1 | |
| SCHEMBL6778818 | 0.85 | HDAC3 (0.47) | TLR7TLR8DRD2DRD4DRD3 | |
| SCHEMBL6768615 | 0.85 | TLR7 (0.39) | TLR7TLR8TP53MAPT | |
| SCHEMBL6774230 | 0.85 | TLR7 (0.44) | BRD4TLR7TLR8DRD2DRD4 | |
| SCHEMBL6775047 | 0.84 | TLR7 (0.44) | BRD4TLR7TLR8DRD2DRD4 | |
| SCHEMBL6772805 | 0.83 | TRPV1 (0.44) | BRD4TLR7TLR8NPC1RAB9A | |
| SCHEMBL6096076 | 0.83 | TLR7 (0.45) | TLR7TLR8RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |