Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768615 | 0.92 | TLR7 (0.39) | TP53TLR7HDAC3HDAC1TLR8 | |
| SCHEMBL6779395 | 0.91 | TLR7 (0.46) | TP53MEN1KMT2ATLR7HDAC3 | |
| SCHEMBL6772889 | 0.91 | SMN1; SMN2 (0.48) | GAAHTTMEN1KMT2AHDAC3 | |
| SCHEMBL6772805 | 0.89 | TRPV1 (0.44) | TLR7HDAC3HDAC1BRD4TLR8 | |
| SCHEMBL6778818 | 0.88 | HDAC3 (0.47) | TP53MEN1KMT2ATLR7HDAC3 | |
| SCHEMBL6774328 | 0.87 | BRD4 (0.41) | TP53MEN1KMT2ATLR7BRD4 | |
| SCHEMBL6774215 | 0.86 | TLR8 (0.54) | TP53MEN1KMT2ATLR7HDAC3 | |
| SCHEMBL6096076 | 0.85 | TLR7 (0.45) | GAATLR7TLR8 | |
| SCHEMBL6778546 | 0.85 | ALDH1A1 (0.45) | TP53TLR7HDAC3HDAC1TLR8 | |
| SCHEMBL6771963 | 0.85 | MAPT (0.46) | TP53GAAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |