Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776784 | 0.91 | ALDH1A1 (0.48) | ALDH1A1HSD17B10GLAHPGDKDM4E | |
| SCHEMBL6772950 | 0.85 | FAAH (0.53) | ALDH1A1HSD17B10GLAHPGDKDM4E | |
| SCHEMBL6782875 | 0.84 | MAPT (0.47) | ALDH1A1HSD17B10MAPTMEN1LMNA | |
| SCHEMBL6778469 | 0.84 | HDAC3 (0.45) | ALDH1A1HSD17B10GLAHPGDKDM4E | |
| SCHEMBL6777601 | 0.83 | MEN1 (0.48) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6773506 | 0.80 | NPC1 (0.47) | ALDH1A1HSD17B10KDM4EGAAMAPT | |
| SCHEMBL6781809 | 0.80 | POLB (0.42) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL6779590 | 0.79 | MAPKAPK2 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6778719 | 0.79 | KMT2A (0.48) | ALDH1A1HSD17B10MAPTLMNAHTT | |
| SCHEMBL6774657 | 0.79 | MAPT (0.49) | ALDH1A1GLAHPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |