Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 12/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773506 | 0.94 | NPC1 (0.47) | CCR3RAB9ANPC1MAPTKDM4E | |
| SCHEMBL6772950 | 0.89 | FAAH (0.53) | CCR3RAB9AMAPTKDM4EFAAH | |
| SCHEMBL6778719 | 0.88 | KMT2A (0.48) | CCR3RAB9ANPC1MAPTHTR2A | |
| SCHEMBL6778012 | 0.88 | CCR3 (0.45) | CCR3RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL6781852 | 0.87 | CCR3 (0.42) | CCR3RAB9ANPC1MAPTHTR2A | |
| SCHEMBL6776742 | 0.87 | CCR3 (0.48) | CCR3RAB9ANPC1HTR2ASMN1; SMN2 | |
| SCHEMBL6776784 | 0.83 | ALDH1A1 (0.48) | KDM4EKMT2AFAAHLMNAPOLB | |
| SCHEMBL6777932 | 0.82 | MAPT (0.43) | CCR3RAB9ANPC1MAPTHTR2A | |
| SCHEMBL6777152 | 0.82 | MAPT (0.45) | CCR3NPC1MAPTKDM4EKMT2A | |
| SCHEMBL6782875 | 0.82 | MAPT (0.47) | CCR3RAB9ANPC1MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |