Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773902 | 0.94 | ALDH1A1 (0.44) | HPGDALOX15HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6773093 | 0.84 | KMT2A (0.51) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6779320 | 0.81 | ALDH1A1 (0.46) | HPGDALOX15HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6773389 | 0.79 | HPGD (0.43) | HPGDALOX15HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6778680 | 0.78 | HPGD (0.43) | HPGDKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6774292 | 0.78 | ALDH1A1 (0.47) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6774657 | 0.77 | MAPT (0.49) | HPGDKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6110335 | 0.77 | KDM4E (0.39) | HPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6110768 | 0.76 | KDM4E (0.38) | HPGDKDM4EALDH1A1 | |
| SCHEMBL6784702 | 0.76 | CYP2C9 (0.46) | ALDH1A1TSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |