Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773547 | 0.85 | PFKFB3 (0.40) | PFKFB3PFKFB4NMT1ITGB3ITGAV | |
| SCHEMBL6773554 | 0.78 | SLC2A1 (0.38) | NMT1ITGB3ITGAVSMN1; SMN2HDAC1 | |
| SCHEMBL6180441 | 0.78 | ITGB3 (0.56) | ITGB3ITGAV | |
| SCHEMBL3772416 | 0.70 | HDAC1 (0.72) | HDAC1 | |
| SCHEMBL4605920 | 0.70 | GAA (0.53) | TDP1 | |
| SCHEMBL9997105 | 0.69 | PFKFB3 (0.61) | FFAR1PFKFB3FFAR4POLBTDP1 | |
| SCHEMBL14532384 | 0.67 | GHSR (0.57) | HTR6FABP4ITGB3ITGAVSMN1; SMN2 | |
| SCHEMBL30315220 | 0.67 | GHSR (0.57) | HTR6FABP4ITGB3ITGAVSMN1; SMN2 | |
| SCHEMBL8371139 | 0.66 | ITGB3 (0.57) | HTR6FABP4POLBTDP1ITGB3 | |
| SCHEMBL14532378 | 0.66 | ITGB3 (0.57) | HTR6FABP4POLBTDP1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677360-B2 | TREATMENT AND PROPHYLAXIS OF CANCER, ARTERIOSCLEROSIS, RESTENOSIS, OSTEOPOROSIS AND EYE DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |