Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.40 |
| ▸ | NMT1 | P30419 | 5/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGAV | P06756 | 3/20 | 0.37 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773550 | 0.85 | FFAR1 (0.48) | PFKFB3NMT1ITGB3ITGAVPFKFB4 | |
| SCHEMBL6773554 | 0.83 | SLC2A1 (0.38) | NMT1ITGB3ITGAVNAMPT | |
| SCHEMBL6180441 | 0.80 | ITGB3 (0.56) | ITGB3ITGAV | |
| SCHEMBL3772416 | 0.67 | HDAC1 (0.72) | — | |
| SCHEMBL8371142 | 0.66 | PFKFB3 (0.43) | PFKFB3 | |
| SCHEMBL4605920 | 0.66 | GAA (0.53) | — | |
| SCHEMBL14290772 | 0.65 | CTSK (0.48) | — | |
| SCHEMBL3802084 | 0.65 | HDAC1 (0.46) | — | |
| SCHEMBL6500176 | 0.63 | SMN1; SMN2 (0.55) | PTGS2 | |
| SCHEMBL2309035 | 0.62 | POLB (0.57) | PFKFB3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677360-B2 | TREATMENT AND PROPHYLAXIS OF CANCER, ARTERIOSCLEROSIS, RESTENOSIS, OSTEOPOROSIS AND EYE DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |