SCHEMBL677382

SCHEMBL677382

CNc1ccc(-c2ccc(NC(=O)c3cccc(C(=O)Nc4ccc(O)c(NC(=O)c5cccc(C(C)=O)c5)c4)c3)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.45
RAB9A P51151 1/20 0.45
POLB P06746 3/20 0.44
CTDSP1 Q9GZU7 2/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
BRAF P15056 5/20 0.43
RXFP1 Q9HBX9 1/20 0.42
KCNK3 O14649 1/20 0.42
KCNK9 Q9NPC2 1/20 0.42
CSF1R P07333 2/20 0.42
TMPRSS4 Q9NRS4 1/20 0.42
ADRB2 P07550 1/20 0.41
PABPC1 P11940 1/20 0.41
DUSP3 P51452 1/20 0.41
PTPN5 P54829 1/20 0.41
PTPN11 Q06124 1/20 0.41
EIF4H Q15056 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108329 0.94 MAPT (0.47) MAPTLMNAGAARAB9APOLB
SCHEMBL1108314 0.87 KCNMA1 (0.52) MAPTGAARAB9APOLBCTDSP1
SCHEMBL13967731 0.86 MAPT (0.47) MAPTLMNAGAARAB9APOLB
SCHEMBL22199855 0.82 KMT2A (0.56) MAPTLMNAGAARAB9APOLB
SCHEMBL677398 0.81 KMT2A (0.48) MAPTGAARAB9APOLBCTDSP1
SCHEMBL14025294 0.78 PTGS1 (0.42) MAPTLMNAGAARAB9AKMT2A
SCHEMBL676656 0.78 AR (0.53) RAB9APOLBKMT2AMEN1BRAF
SCHEMBL676658 0.78 KMT2A (0.49) MAPTGAARAB9APOLBCTDSP1
SCHEMBL1108328 0.78 AR (0.53) RAB9APOLBKMT2AMEN1BRAF
SCHEMBL677387 0.78 KMT2A (0.48) MAPTGAARAB9APOLBCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7906213-B2 Epoxy resin curable composition for prepreg ADEKA CORPORATION (JP) 2011-03-15 US disclosed
US-20090030147-A1 Epoxy Resin Curable Composition For Prepreg ADEKA CORPORATION (JP) 2009-01-29 US disclosed