Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285069 | 0.93 | TLR7 (0.48) | TLR7TLR8NUDT1ADORA2AADORA2B | |
| SCHEMBL6780401 | 0.92 | TLR7 (0.38) | TLR7TLR8NUDT1ADORA2AADORA2B | |
| SCHEMBL6774273 | 0.90 | TLR7 (0.38) | TLR7TLR8NUDT1ADORA2AADORA2B | |
| SCHEMBL6779139 | 0.90 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6784556 | 0.87 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6780506 | 0.86 | ALDH1A1 (0.46) | TLR7 | |
| SCHEMBL6096076 | 0.85 | TLR7 (0.45) | TLR7TLR8NUDT1 | |
| SCHEMBL6780360 | 0.85 | ALDH1A1 (0.39) | TLR7 | |
| SCHEMBL6773764 | 0.84 | TLR7 (0.38) | TLR7TLR8 | |
| SCHEMBL6779376 | 0.84 | HTR7 (0.38) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |