Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774083 | 0.85 | TLR7 (0.40) | TLR7 | |
| SCHEMBL6285069 | 0.84 | TLR7 (0.48) | TLR7 | |
| SCHEMBL6784556 | 0.84 | TLR7 (0.40) | ALDH1A1TLR7CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL6779139 | 0.83 | TLR7 (0.44) | ALDH1A1TLR7 | |
| SCHEMBL6773764 | 0.83 | TLR7 (0.38) | ALDH1A1TLR7HTR2AHTR7HTR6 | |
| SCHEMBL6779163 | 0.83 | SCN1A (0.44) | ALDH1A1TLR7CYP2C9CYP2C19NPY5R | |
| SCHEMBL6778162 | 0.83 | TLR7 (0.41) | ALDH1A1TP53TLR7CYP2C9CYP2C19 | |
| SCHEMBL6779376 | 0.83 | HTR7 (0.38) | ALDH1A1TLR7HTR2AHTR7HTR6 | |
| SCHEMBL6778982 | 0.82 | TLR7 (0.40) | ALDH1A1TP53TLR7CYP2C9CYP2C19 | |
| SCHEMBL6780506 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TLR7HTR2AHTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |