Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778739 | 0.88 | TLR7 (0.40) | TLR7ALDH1A1TLR8POLB | |
| SCHEMBL6778344 | 0.87 | TLR7 (0.36) | TLR7ALDH1A1TLR8LMNA | |
| SCHEMBL6784556 | 0.86 | TLR7 (0.40) | TLR7ALDH1A1SMN1; SMN2TLR8KMT2A | |
| SCHEMBL6779376 | 0.85 | HTR7 (0.38) | TLR7HTR7HTR6HTR2AALDH1A1 | |
| SCHEMBL6780506 | 0.85 | ALDH1A1 (0.46) | TLR7HTR7HTR2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6777494 | 0.85 | DRD2 (0.39) | TLR7HTR7DRD2HTR6HTR2A | |
| SCHEMBL6774083 | 0.84 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6784344 | 0.84 | TLR7 (0.40) | TLR7HTR7DRD2HTR6HTR2A | |
| SCHEMBL6783636 | 0.84 | TLR7 (0.39) | TLR7HTR7DRD2HTR6HTR2A | |
| SCHEMBL6780023 | 0.84 | TLR7 (0.42) | TLR7ALDH1A1TLR8POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |