Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
| ▸ | UGCG | Q16739 | 2/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769659 | 0.88 | L3MBTL1 (0.38) | L3MBTL1TDP1KDM4EPOLBMEN1 | |
| SCHEMBL6769752 | 0.87 | LTB4R (0.42) | LTB4R | |
| SCHEMBL6768709 | 0.87 | LTB4R (0.42) | LTB4R | |
| SCHEMBL6775391 | 0.86 | S1PR1 (0.38) | — | |
| SCHEMBL383869 | 0.84 | L3MBTL1 (0.43) | L3MBTL1TDP1KDM4EPOLBMEN1 | |
| SCHEMBL6769593 | 0.82 | L3MBTL1 (0.35) | L3MBTL1TDP1KDM4EPOLBLTB4R | |
| SCHEMBL6767982 | 0.74 | LTB4R (0.39) | LTB4R | |
| SCHEMBL6769532 | 0.74 | S1PR1 (0.37) | — | |
| SCHEMBL6890392 | 0.73 | L3MBTL1 (0.35) | L3MBTL1KDM4EPOLB | |
| SCHEMBL6768150 | 0.72 | POLB (0.37) | L3MBTL1TDP1KDM4EPOLBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | claimed |