Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 8/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769752 | 1.00 | LTB4R (0.42) | LTB4RTNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL6767982 | 0.87 | LTB4R (0.39) | LTB4RTNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL6774202 | 0.87 | L3MBTL1 (0.39) | LTB4R | |
| SCHEMBL6775391 | 0.85 | S1PR1 (0.38) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL386098 | 0.82 | TNNC1 (0.42) | LTB4RTNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL6309871 | 0.82 | TNNC1 (0.42) | LTB4RTNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL13165876 | 0.81 | LTB4R (0.42) | LTB4R | |
| SCHEMBL6303133 | 0.80 | TNNC1 (0.40) | LTB4RTNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL6767901 | 0.78 | GRM5 (0.39) | LTB4R | |
| SCHEMBL7716311 | 0.77 | MAOA (0.47) | LTB4RTNNC1S1PR1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | claimed |