SCHEMBL677427

SCHEMBL677427

CCCCC1=C([Hf](Cc2ccccc2)(Cc2ccccc2)C2=C(CCCC)C=CC2)CC=C1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
DNM1 Q05193 2/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
HTT P42858 2/20 0.32
KCNH2 Q12809 1/20 0.32
HSD11B1 P28845 1/20 0.31
CETP P11597 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482717 0.74
SCHEMBL3861600 0.73 SIGMAR1 (0.39) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL29023871 0.73
SCHEMBL5374597 0.73
SCHEMBL299733 0.72 SIGMAR1 (0.38) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL4465789 0.72 SIGMAR1 (0.38) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL28350421 0.71 KCNH2 (0.35) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL27695102 0.71 KCNH2 (0.35) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL27489592 0.71 SIGMAR1 (0.34) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL8336271 0.71 SIGMAR1 (0.34) SIGMAR1DNM1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285893-B2 POLYMER COMPOSITIONS HAVING IMPROVED HOMOGENEITY AND ODOUR, A METHOD FOR MAKING THEM AND PIPES MADE THEREOF BOREALIS AG (AT) 2017-09-06 EP claimed
EP-2285897-B2 POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM BOREALIS AG (AT) 2015-08-26 EP claimed
US-8557924-B2 Polymer compositions and pressure-resistant pipes made therefrom BOREALIS AG (AT) 2013-10-15 US claimed
EP-2285897-B1 POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM BOREALIS AG (AT) 2011-12-07 EP claimed
EP-2285893-B1 POLYMER COMPOSITIONS HAVING IMPROVED HOMOGENEITY AND ODOUR, A METHOD FOR MAKING THEM AND PIPES MADE THEREOF BOREALIS AG (AT) 2011-09-21 EP claimed
US-20110108121-A1 Polymer Compositions and Pressure-Resistant Pipes Made Therefrom BOREALIS AG (AU) 2011-05-12 US claimed
US-20110091674-A1 Polymer Compositions Having Improved Homogeneity and Odour, A Method For Making Them and Pipes Made Thereof BOREALIS AG (AT) 2011-04-21 US claimed
EP-2285897-A1 POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM Borealis AG (AT) 2011-02-23 EP claimed
WO-2009147023-A1 POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM BOREALIS AG (AT) 2009-12-10 WO claimed
EP-2130862-A1 Polymer compositions and pressure-resistant pipes made thereof Borealis AG (AT) 2009-12-09 EP claimed
EP-3234954-B1 POLYMER COMPOSITION FOR W&C APPLICATION WITH ADVANTAGEOUS ELECTRICAL PROPERTIES BOREALIS GMBH (AT) 2025-09-10 EP disclosed
WO-2025125458-A1 MODIFIED POLYETHYLENE HAVING IMPROVED HYDROSTATIC PRESSURE RESISTANCE AND SLOW CRACK GROWTH RESISTANCE ABU DHABI POLYMERS CO. LTD (BOROUGE) - SOLE PROPRIETORSHIP L.L.C. (AE) 2025-06-19 WO disclosed
US-20240309125-A1 POLYETHYLENE FOR USE IN THE PRODUCTION OF CROSSLINKED POLYETHYLENE (PEX) BOREALIS AG (AT) 2024-09-19 US disclosed
US-11783960-B2 Power cable polymer composition comprising thermoplastic and having advantageous properties BOREALIS AG (AT) 2023-10-10 US disclosed
US-11410788-B2 Polymer composition for W and C application with advantageous electrical properties BOREALIS AG (AT) 2022-08-09 US disclosed
WO-2009147023-A1 POLYMER COMPOSITIONS AND PRESSURE-RESISTANT PIPES MADE THEREFROM BOREALIS AG (AT) 2009-12-10 WO disclosed
WO-2009147022-A1 HIGH DENSITY POLYMER COMPOSITIONS, A METHOD FOR THEIR PREPARATION AND PRESSURE-RESISTANT PIPES MADE THEREFROM BOREALIS AG (AT) 2009-12-10 WO disclosed
EP-2130863-A1 High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom Borealis AG (AT) 2009-12-09 EP disclosed
EP-2130859-A1 Polymer compositions having improved homogeneity and odour, a method for making them and pipes made thereof Borealis AG (AT) 2009-12-09 EP disclosed
EP-2130862-A1 Polymer compositions and pressure-resistant pipes made thereof Borealis AG (AT) 2009-12-09 EP disclosed