SCHEMBL8336271

SCHEMBL8336271

CCCCC1=C([Zr](Cc2ccccc2)(Cc2ccccc2)C2=C(CCCC)C=CC2)CC=C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
DNM1 Q05193 2/20 0.33
CETP P11597 1/20 0.33
HPGD P15428 2/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
HDAC3 O15379 1/20 0.32
HTT P42858 2/20 0.32
KCNH2 Q12809 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424708 0.79
SCHEMBL8895456 0.79 CETP (0.32) CETPHPGDORAI1ORAI2ORAI3
SCHEMBL796908 0.78
SCHEMBL5495119 0.75 LTA4H (0.35) HPGDMAPK1SMN1; SMN2HTTKCNH2
SCHEMBL4014819 0.74 ALDH1A1 (0.32) HPGDALDH1A1HSD17B10
SCHEMBL28423016 0.73 THRA (0.30)
SCHEMBL3861600 0.73 SIGMAR1 (0.39) SIGMAR1DNM1CETPHPGDPOLB
SCHEMBL797700 0.73
SCHEMBL4455565 0.73
SCHEMBL299733 0.72 SIGMAR1 (0.38) SIGMAR1DNM1CETPPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026115-B Multi-head or double-head composition capable of being used for chain shuttling and preparation method thereof 陶氏环球技术有限责任公司 2021-11-09 CN disclosed
US-5928825-A EXHIBITS RELEASE PROPERTIES AT A LOWER TEMPERATURE, HAS SATISFACTORY ANTI-OFFSET PROPERTIES, EXCELLENT POWDER FLUIDITY AND UNDERGOES NO BLOCKING PHENOMENON UNDER HIGH TEMPERATURE AND HUMIDITY FUJI XEROX CO., LTD. (JP) 1999-07-27 US disclosed
US-5650254-A ELECTROSTATIC LATENT IMAGE FUJI XEROX CO., LTD, (JP) 1997-07-22 US disclosed
EP-0619326-B1 Olefin polymerization catalyst and olefin polymerisation process TOSOH CORP (JP) 1997-06-25 EP disclosed
EP-0619326-A1 Olefin polymerization catalyst and olefin polymerisation process TOSOH CORPORATION (JP) 1994-10-12 EP disclosed