Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 6/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773196 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL6098139 | 0.86 | DYRK1A (0.37) | ADCY5ALDH1A1TDP1TK1 | |
| SCHEMBL6784160 | 0.85 | EPHX1 (0.38) | BRD4TLR7ADCY5ALDH1A1POLB | |
| SCHEMBL14592749 | 0.83 | TLR7 (0.58) | BRD4TLR7NPC1RAB9AMAPT | |
| SCHEMBL6777509 | 0.83 | FAAH (0.47) | DRD2DRD3MAPTALDH1A1 | |
| SCHEMBL6778549 | 0.82 | KDM4E (0.38) | BRD4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6777814 | 0.81 | EPHX1 (0.44) | — | |
| SCHEMBL6775246 | 0.81 | HDAC1 (0.41) | ADCY5ALDH1A1TDP1 | |
| SCHEMBL6773535 | 0.80 | NAAA (0.40) | DRD2DRD3SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6768483 | 0.80 | DRD3 (0.44) | DRD2DRD3TLR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |