Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775246 | 0.89 | HDAC1 (0.41) | ALDH1A1TDP1ADORA2AKMT2AHDAC1 | |
| SCHEMBL6098139 | 0.88 | DYRK1A (0.37) | ALDH1A1TDP1 | |
| SCHEMBL6775784 | 0.87 | DRD2 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL6784160 | 0.87 | EPHX1 (0.38) | ALDH1A1TDP1EPHX1ADORA2AKMT2A | |
| SCHEMBL6777509 | 0.85 | FAAH (0.47) | ALDH1A1EPHX1KMT2AHDAC1 | |
| SCHEMBL6778549 | 0.84 | KDM4E (0.38) | ALDH1A1 | |
| SCHEMBL6777814 | 0.83 | EPHX1 (0.44) | EPHX1 | |
| SCHEMBL6773535 | 0.82 | NAAA (0.40) | ALDH1A1KMT2A | |
| SCHEMBL6768483 | 0.82 | DRD3 (0.44) | ALDH1A1KMT2AHDAC1HDAC2 | |
| SCHEMBL6778610 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TDP1ADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |