SCHEMBL67758

SCHEMBL67758

Cc1ccc(C(C)(C)c2ccc(C)cc2O)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.54
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 2/20 0.46
LMNA P02545 4/20 0.45
CHRM1 P11229 1/20 0.45
SLC6A2 P23975 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR2B P41595 1/20 0.45
ALDH1A1 P00352 7/20 0.45
MAPT P10636 3/20 0.45
POLB P06746 2/20 0.45
ALOX15 P16050 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP1A2 P05177 1/20 0.44
ATP2A2 P16615 1/20 0.44
ATP2A3 Q93084 1/20 0.44
HSD17B10 Q99714 3/20 0.43
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30250486 1.00 TRPA1 (0.54) TRPA1TDP1TP53LMNACHRM1
SCHEMBL180815 0.88 ALDH1A1 (0.59) TRPA1TDP1TP53LMNACHRM1
SCHEMBL15485283 0.88 ALDH1A1 (0.59) TRPA1TDP1TP53LMNACHRM1
SCHEMBL29362726 0.88 ALDH1A1 (0.59) TRPA1TDP1TP53LMNACHRM1
Hydrogen Sulfide SCHEMBL28854683 0.86 ALDH1A1 (0.56) TRPA1TDP1TP53LMNACHRM1
SCHEMBL30211783 0.86 ALDH1A1 (0.56) TRPA1TDP1TP53LMNACHRM1
SCHEMBL29477942 0.86 ALDH1A1 (0.56) TRPA1TDP1TP53LMNACHRM1
Ammonia Solution, Strong SCHEMBL28261251 0.86 ALDH1A1 (0.56) TRPA1TDP1TP53LMNACHRM1
Potassium SCHEMBL29477970 0.86 ALDH1A1 (0.56) TRPA1TDP1TP53LMNACHRM1
SCHEMBL22652590 0.84 TRPA1 (0.52) TRPA1TDP1TP53LMNACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4351957-A Process for preparing diaminodiphenyl-alkanes THE UPJOHN COMPANY (US) 1982-09-28 US claimed
US-20230149323-A1 INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS ORPHA BIOTECH S.R.L. (IT) 2023-05-18 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4351957-A Process for preparing diaminodiphenyl-alkanes THE UPJOHN COMPANY (US) 1982-09-28 US disclosed
US-3979180-A PHENOL, DIPHENYLAMINE, THIOPHOSPHATES, TRANSITION METAL NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TRPA1 150/4885TDP1 3534/4885TP53 1492/4885
US-20230149323-A1 INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS FPR3, FPR1, PLAUR TRPA1 928/4885TDP1 3144/4885TP53 3970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.