Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 9/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774597 | 0.89 | TAS2R14 (0.47) | TAS2R14MAPK1MEN1KMT2AMAPT | |
| SCHEMBL29238388 | 0.82 | KMT2A (0.56) | MEN1KMT2ANPSR1ALDH1A1PTPN1 | |
| SCHEMBL2865693 | 0.78 | KMT2A (0.46) | MEN1KMT2AALDH1A1PTPN1NPC1 | |
| SCHEMBL23257709 | 0.77 | MEN1 (0.64) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL16558062 | 0.76 | KMT2A (0.52) | MAPK1MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL13136199 | 0.75 | THRB (0.46) | TAS2R14MAPK1MEN1KMT2AMAPT | |
| SCHEMBL6773852 | 0.75 | NPY5R (0.65) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL6773850 | 0.75 | NPY5R (0.65) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL20269611 | 0.75 | ALDH1A1 (0.44) | TAS2R14MAPK1MEN1KMT2AMAPT | |
| SCHEMBL15779237 | 0.72 | PTPN1 (0.56) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683055-B1 | GUANIDINE OR AMIDINE TERMINED PEPTIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |