Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.58 |
| ▸ | CHKA | P35790 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571246 | 0.89 | CHKA (0.50) | CCR2CHKA | |
| SCHEMBL8458456 | 0.86 | CCR2 (0.65) | CCR2LMNA | |
| SCHEMBL6776140 | 0.85 | CHKA (0.55) | CCR2CHKA | |
| SCHEMBL6770077 | 0.81 | CCR2 (0.65) | CCR2LMNA | |
| SCHEMBL22516895 | 0.78 | CCR2 (0.59) | CCR2CHKALMNA | |
| Hydrochloric Acid SCHEMBL8479099 | 0.78 | KMT2A (0.63) | LMNA | |
| SCHEMBL3032788 | 0.77 | NPC1 (0.66) | LMNA | |
| SCHEMBL8236801 | 0.77 | HRH3 (0.64) | CCR2LMNA | |
| SCHEMBL5483874 | 0.75 | SMN1; SMN2 (0.61) | LMNA | |
| SCHEMBL23775497 | 0.74 | CCR2 (0.59) | CCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-0914319-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997044329-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1997-11-27 | — | — | WO | disclosed |