Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 14/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458456 | 0.87 | CCR2 (0.65) | CCR2LMNA | |
| SCHEMBL4512612 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KMT2AGFER | |
| SCHEMBL6776114 | 0.81 | CCR2 (0.58) | CCR2LMNA | |
| Hydrochloric Acid SCHEMBL3844581 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KMT2AGFER | |
| SCHEMBL6765717 | 0.80 | CCR2 (0.51) | CCR2 | |
| SCHEMBL5373264 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2AGFER | |
| SCHEMBL2725965 | 0.79 | KMT2A (0.90) | ALDH1A1KMT2AGFER | |
| SCHEMBL31093108 | 0.77 | KMT2A (0.74) | ALDH1A1KMT2AGFER | |
| SCHEMBL14578035 | 0.77 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2A | |
| SCHEMBL10507206 | 0.76 | ALDH1A1 (0.96) | ALDH1A1KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-0914319-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997044329-A9 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997044329-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1997-11-27 | — | — | WO | disclosed |