Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.61 |
| ▸ | USP7 | Q93009 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782138 | 0.90 | KDM4E (0.59) | MEN1KMT2AMDM2USP7RXFP1 | |
| SCHEMBL6784907 | 0.88 | MEN1 (0.65) | MEN1KMT2AMDM2RXFP1KDM4E | |
| SCHEMBL6779535 | 0.86 | MEN1 (0.80) | MEN1KMT2AUSP7RXFP1ATM | |
| SCHEMBL6781607 | 0.84 | MEN1 (1.00) | MEN1KMT2AUSP7RXFP1ATM | |
| SCHEMBL6781529 | 0.81 | MEN1 (0.72) | MEN1KMT2AUSP7RXFP1ATM | |
| SCHEMBL6780926 | 0.79 | MEN1 (0.68) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL3706089 | 0.79 | USP7 (0.66) | MEN1KMT2AMDM2USP7RXFP1 | |
| SCHEMBL3705385 | 0.78 | USP7 (0.79) | MEN1KMT2AMDM2USP7RXFP1 | |
| SCHEMBL6779640 | 0.78 | ALDH1A1 (0.76) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL3709475 | 0.77 | KDM4E (0.59) | MEN1KMT2AMDM2USP7RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |