Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | POLB | P06746 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | FPR1 | P21462 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779753 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6780486 | 0.82 | ALDH1A1 (0.75) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6784907 | 0.82 | MEN1 (0.65) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6782138 | 0.79 | KDM4E (0.59) | ALDH1A1KDM4ETDP1ALOX15HTT | |
| SCHEMBL6776151 | 0.78 | MEN1 (0.73) | ALDH1A1KDM4ETDP1ALOX15HTT | |
| SCHEMBL6781021 | 0.72 | CCR2 (0.67) | ALDH1A1KDM4E | |
| SCHEMBL3709475 | 0.69 | KDM4E (0.59) | ALDH1A1KDM4EPOLBTDP1FPR1 | |
| SCHEMBL6779502 | 0.68 | MEN1 (0.82) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6780926 | 0.67 | MEN1 (0.68) | ALDH1A1KDM4ETDP1ALOX15TSHR | |
| SCHEMBL6785761 | 0.67 | MEN1 (0.71) | ALDH1A1KDM4EPOLBTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |