Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772318 | 0.93 | ALDH1A1 (0.48) | TLR7TLR8NUDT1PPARGALDH1A1 | |
| SCHEMBL6783392 | 0.89 | TLR7 (0.47) | TLR7TLR8NUDT1ALDH1A1LMNA | |
| SCHEMBL6777785 | 0.89 | TLR7 (0.41) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6776452 | 0.86 | TLR7 (0.46) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL4793106 | 0.85 | FBP1 (0.45) | TLR7TLR8PPARGALDH1A1LMNA | |
| SCHEMBL6773544 | 0.84 | TLR7 (0.51) | TLR7TLR8NUDT1 | |
| SCHEMBL6780460 | 0.84 | TLR7 (0.44) | TLR7TLR8NUDT1ALDH1A1LMNA | |
| SCHEMBL5750412 | 0.84 | TLR8 (0.58) | TLR7TLR8NUDT1PPARG | |
| SCHEMBL6782361 | 0.84 | PTGER4 (0.42) | TLR7TLR8PPARGALDH1A1LMNA | |
| SCHEMBL6778701 | 0.83 | TLR7 (0.40) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |