SCHEMBL677658

SCHEMBL677658

O=NN(O)C(O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 3/20 0.38
SRC P12931 2/20 0.38
CYP2D6 P10635 1/20 0.38
ALOX15 P16050 1/20 0.38
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
ALOX5 P09917 1/20 0.37
KDM4E B2RXH2 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6522565 0.74 LMNA (0.44) LMNAMAPK1ALDH1A1CYP2D6KDM4E
SCHEMBL31480056 0.71 LMNA (0.46) LMNAMAPK1ALDH1A1SRCCYP2D6
SCHEMBL11511432 0.68 LMNA (0.39) LMNAMAPK1ALDH1A1KDM4ETSHR
SCHEMBL1674631 0.67 KDM4E (0.58) LMNAALDH1A1KDM4E
SCHEMBL13169041 0.67 LMNA (0.48) LMNAMAPK1ALDH1A1SRCCYP2D6
SCHEMBL7960004 0.64 LMNA (0.44) LMNAMAPK1ALDH1A1CYP2D6KDM4E
SCHEMBL21416132 0.64 LMNA (0.46) LMNAMAPK1ALDH1A1CYP2D6KDM4E
SCHEMBL10430789 0.64 AOC3 (0.61) LMNAKDM4E
SCHEMBL1038340 0.63
SCHEMBL11630254 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190142940-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2019-05-16 US disclosed
US-9744237-B2 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2017-08-29 US disclosed
US-20120207809-A1 Method and system for effecting changes in pigmented tissue MOAZED KAMBIZ THOMAS (US) 2012-08-16 US disclosed
US-20120076848-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2012-03-29 US disclosed
US-20110280909-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-11-17 US disclosed
WO-2011011065-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2011-01-27 WO disclosed
WO-2010087983-A1 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE MOAZED KAMBIZ THOMAS (US) 2010-08-05 WO disclosed