Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522565 | 0.77 | LMNA (0.44) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL4786970 | 0.74 | LMNA (0.41) | LMNAMAPK1SLC6A2SLC6A4KDM4E | |
| SCHEMBL9353616 | 0.74 | ALOX5 (0.52) | LMNAKDM4EALDH1A1ADRA2AADRA2C | |
| SCHEMBL31480056 | 0.74 | LMNA (0.46) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL9354511 | 0.73 | ALOX5 (0.41) | LMNASLC6A2SLC6A4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28637822 | 0.72 | NPSR1 (0.40) | LMNAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1674631 | 0.70 | KDM4E (0.58) | LMNASLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL6399613 | 0.70 | ALDH1A1 (0.44) | LMNAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11141579 | 0.70 | LMNA (0.47) | LMNASLC6A2SLC6A4ALDH1A1TSHR | |
| SCHEMBL449664 | 0.70 | NPSR1 (0.44) | LMNAMAPK1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |