SCHEMBL7960004

SCHEMBL7960004

[CH2]C(O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41
HIF1A Q16665 1/20 0.41
AOC3 Q16853 3/20 0.40
CYP2D6 P10635 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7948508 0.80 LMNA (0.45) LMNAMAPK1KDM4EALDH1A1TSHR
SCHEMBL4472225 0.78 LMNA (0.52) LMNAMAPK1KDM4EALDH1A1TSHR
SCHEMBL1759610 0.77
SCHEMBL1759718 0.77
SCHEMBL118951 0.77
SCHEMBL4348933 0.77 LMNA (0.48) LMNAMAPK1KDM4ETSHRL3MBTL1
SCHEMBL448348 0.75 DPP4 (0.53) LMNAMAPK1TSHRCYP2D6
Hydrochloric Acid SCHEMBL8380204 0.74 ALDH1A1 (0.46) LMNAMAPK1KDM4EALDH1A1TSHR
SCHEMBL28466803 0.74 LMNA (0.48) LMNAMAPK1KDM4EALDH1A1TSHR
SCHEMBL453395 0.72 DPP4 (0.52) LMNAMAPK1KDM4EALDH1A1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105785720-B Photosensitive resin composition, photocured pattern formed therefrom, and image display device having the same 东友精细化工有限公司 2020-02-07 CN claimed
CN-108084002-A A kind of preparation method of 2- hydroxy phenyls propiophenone 常州瑞明药业有限公司 2018-05-29 CN claimed
CN-105988288-B Photosensitive resin composition, photocured pattern and image display device 东友精细化工有限公司 2021-05-28 CN disclosed
CN-105842988-B Photosensitive resin composition, photocured pattern formed by photosensitive resin composition and image display device with photocured pattern 东友精细化工有限公司 2020-11-27 CN disclosed
CN-105842987-B Photosensitive resin composition, photocured pattern formed by photosensitive resin composition and image display device with photocured pattern 东友精细化工有限公司 2020-11-13 CN disclosed
CN-105785720-B Photosensitive resin composition, photocured pattern formed therefrom, and image display device having the same 东友精细化工有限公司 2020-02-07 CN disclosed
CN-101205268-B Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP 2010-09-29 CN disclosed
CN-101205268-A Method for hydrogenating conjugated diene polymer and hydrogenation catalyst composition TSRC CORP (CN) 2008-06-25 CN disclosed
US-6323235-B1 CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS OHTAKE ATSUSHI (JP) 2001-11-27 US disclosed
US-6043264-A A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA TORAY INDUSTRIES, INC. (JP) 2000-03-28 US disclosed
US-5760235-A DIPEPTIDES BASED ON PROLINE OR PIPECOLIC ACID AND ARGININE ALDEHYDE GYOGYSZERKUTATO INTEZET KFT. (HU) 1998-06-02 US disclosed
CN-1034501-C (Bemzhydryloxyethylpiperidyl) aliphatic acid derivatives and their use in the treatment of allergies and asthma SANKYO CO (JP) 1997-04-09 CN disclosed
EP-0751126-A1 BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME TORAY INDUSTRIES, INC. (JP) 1997-01-02 EP disclosed
US-5420128-A Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-30 US disclosed
EP-0629212-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF. GYOGYSZERKUTATO INTEZET (HU) 1994-12-21 EP disclosed
WO-1993018060-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF Gyógyszerkutató Intézet Kft. (HU) 1993-09-16 WO disclosed
EP-0503099-A1 PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-09-16 EP disclosed
CN-1058773-A (diphenyl-methyl oxyethyl group piperidyl) aliphatic acid derivative and the purposes in treatment allergy and asthma thereof SANKYO CO (JP) 1992-02-19 CN disclosed
CN-1058773-A (diphenyl-methyl oxyethyl group piperidyl) aliphatic acid derivative and the purposes in treatment allergy and asthma thereof SANKYO CO (JP) 1992-02-19 CN disclosed
EP-0441226-A1 (cyanomethyl)pyridines useful as PAF antagonists J. URIACH & CIA. S.A. (ES) 1991-08-14 EP disclosed