SCHEMBL677671

SCHEMBL677671

C=CCOC(=O)CC(O)(CC(=O)O)C(=O)OC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.33
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3800159 0.90 TSHR (0.33) TSHRTDP1PKMSMN1; SMN2ALDH1A1
SCHEMBL2576138 0.87 ALDH1A1 (0.38) TSHRTDP1PKMSMN1; SMN2ALDH1A1
Acetic Acid SCHEMBL9743919 0.84 TSHR (0.41) TSHRTDP1PKMSMN1; SMN2ALDH1A1
SCHEMBL677673 0.83 TSHR (0.38) TSHRTDP1PKMSMN1; SMN2ALDH1A1
Ethylene Glycol SCHEMBL1071330 0.83 TSHR (0.35) TSHRTDP1PKMSMN1; SMN2ALDH1A1
SCHEMBL166756 0.83 ALDH1A1 (0.38) PKMALDH1A1
SCHEMBL173250 0.82 ALDH1A1 (0.54) TSHRTDP1PKMSMN1; SMN2ALDH1A1
SCHEMBL2189860 0.82 ALDH1A1 (0.48) TSHRTDP1ALDH1A1
SCHEMBL8603559 0.81 TSHR (0.38) TSHRTDP1PKMSMN1; SMN2ALDH1A1
SCHEMBL173249 0.80 TSHR (0.42) TSHRTDP1PKMSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200215136-A1 MEDICATION DISPENSING SYSTEM WREATH, INC. 2020-07-09 US claimed
US-20240050632-A1 SELF-EXPANDING DEVICES AND METHODS THEREFOR INTERSECT ENT, INC 2024-02-15 US disclosed
US-11826494-B2 Self-expanding devices and methods therefor INTERSECT ENT, INC. (US) 2023-11-28 US disclosed
US-20230256100-A1 MEDICATION SYSTEM WREATH, INC. 2023-08-17 US disclosed
US-11654216-B2 Self-expanding devices and methods therefor INTERSECT ENT, INC. (US) 2023-05-23 US disclosed
US-11564790-B2 Skin printer Tran, Bao (US) 2023-01-31 US disclosed
US-11491229-B2 Medication system Tran, Bao (US) 2022-11-08 US disclosed
CN-115154424-A Low-hygroscopicity solid dispersion containing sodium valproate, preparation method of low-hygroscopicity solid dispersion and sustained-release tablet core 广州茂丰药业有限公司 2022-10-11 CN disclosed
CN-109627458-B Preparation method of quaternary ammonium group-containing (methyl) acrylate copolymer aqueous dispersion 英德茂丰药业有限公司 2021-11-12 CN disclosed
US-11110210-B2 Self-expanding devices and methods therefor INTERSECT ENT, INC. (US) 2021-09-07 US disclosed
US-20060240065-A1 Compositions for medical devices containing agent combinations in controlled volumes ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2006-10-26 US disclosed
WO-2006078356-A1 POLY(HYDROXYALKANOATE-CO-ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2006-07-27 WO disclosed
US-20060160985-A1 POLY(HYDROXYALKANOATE-CO-ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2006-07-20 US disclosed
WO-2006073631-A1 POLYMERS CONTAINING POLY(HYDROXYALKANOATES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2006-07-13 WO disclosed
US-20060147412-A1 Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2006-07-06 US disclosed
WO-2006057929-A1 BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES BASED ON POLYESTERS AND METHODS FOR FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2006-06-01 WO disclosed
US-20060111546-A1 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2006-05-25 US disclosed
WO-2006031398-A2 COMPOSITIONS CONTAINING FAST-LEACHING PLASTICIZERS FOR IMPROVED PERFORMANCE OF MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2006-03-23 WO disclosed
US-20060058868-A1 Compositions containing fast-leaching plasticizers for improved performance of medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2006-03-16 US disclosed
US-20050288481-A1 Design of poly(ester amides) for the control of agent-release from polymeric compositions ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060147412-A1 Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same PUF60, PLOD3, HGF TSHR 4511/4885TDP1 1328/4885PKM 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.