Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779350 | 0.93 | LMNA (0.41) | LMNAPOLBTLR7TLR8P2RY12 | |
| SCHEMBL6777299 | 0.88 | ALDH1A1 (0.43) | LMNATLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6773368 | 0.85 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6288252 | 0.84 | EPHX2 (0.47) | — | |
| SCHEMBL6768386 | 0.84 | TLR7 (0.42) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6777973 | 0.83 | TLR7 (0.37) | LMNATLR7TLR8NUDT1 | |
| SCHEMBL6772831 | 0.83 | FAAH (0.38) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6778341 | 0.83 | TLR7 (0.35) | TLR7TLR8NUDT1 | |
| SCHEMBL6279887 | 0.82 | TLR7 (0.41) | TLR7TLR8NUDT1P2RY12 | |
| SCHEMBL6773457 | 0.82 | L3MBTL1 (0.42) | POLBTLR7TLR8NUDT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100402528-C | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-16 | — | — | CN | claimed |
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |