Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR7 | P34969 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779745 | 0.90 | ALDH1A1 (0.51) | HTR2AHTR7ALDH1A1PKML3MBTL1 | |
| SCHEMBL6781246 | 0.89 | HTR7 (0.39) | HTR2AHTR7HTR6CCR1ALDH1A1 | |
| SCHEMBL6779513 | 0.87 | ALDH1A1 (0.38) | ALDH1A1PKML3MBTL1 | |
| SCHEMBL6783971 | 0.86 | ALDH1A1 (0.44) | HTR7ALDH1A1PKMMAPK1SMN1; SMN2 | |
| SCHEMBL6774053 | 0.84 | HDAC1 (0.41) | HTR7ALDH1A1PKMMMP1MMP2 | |
| SCHEMBL6773439 | 0.83 | TRPV1 (0.44) | — | |
| SCHEMBL6777386 | 0.82 | CCR1 (0.41) | DRD2HTR2AHTR7HTR6CCR1 | |
| SCHEMBL6778222 | 0.81 | ALDH1A1 (0.40) | DRD2HTR2AHTR7HTR6ALDH1A1 | |
| SCHEMBL6287653 | 0.81 | F2 (0.39) | ALDH1A1NPY5R | |
| SCHEMBL6287659 | 0.81 | F2 (0.39) | ALDH1A1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100372846-C | Sulfonamido substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-03-05 | — | — | CN | claimed |
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |