Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774052 | 0.87 | POLB (0.43) | HDAC3HDAC1HDAC2NPC1RAB9A | |
| SCHEMBL6768483 | 0.85 | DRD3 (0.44) | HDAC3HDAC1TLR7HDAC2NPC1 | |
| SCHEMBL13937489 | 0.84 | TRPV1 (0.47) | TRPV1HDAC3HDAC1PPARDBRD4 | |
| SCHEMBL6777208 | 0.83 | DRD2 (0.41) | — | |
| SCHEMBL6773548 | 0.83 | HDAC3 (0.49) | HDAC3HDAC1HDAC2 | |
| SCHEMBL6773275 | 0.82 | TRPV1 (0.43) | TRPV1HDAC3HDAC1PPARDMCHR1 | |
| SCHEMBL6773542 | 0.82 | TP53BP1 (0.48) | HDAC3HDAC1TLR7HDAC2 | |
| SCHEMBL6772103 | 0.81 | MCHR1 (0.51) | MCHR1NPC1RAB9A | |
| SCHEMBL6780394 | 0.80 | TRPV1 (0.47) | TRPV1HDAC3HDAC1MCHR1TLR7 | |
| SCHEMBL6098139 | 0.79 | DYRK1A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100387597-C | Amido-substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-14 | — | — | CN | claimed |
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |