Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273870 | 0.85 | HIF1A (0.69) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL11593766 | 0.84 | MAPT (0.81) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL30765134 | 0.83 | SMN1; SMN2 (0.62) | HIF1ACA1MAPTRAB9AMEN1 | |
| SCHEMBL6255527 | 0.81 | EGFR (0.71) | MAPTNOX4EGFRSYKHSP90AA1 | |
| SCHEMBL25442713 | 0.81 | HKDC1 (0.70) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL10781073 | 0.79 | MAPT (0.73) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL28133929 | 0.79 | HIF1A (0.61) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL802584 | 0.79 | HIF1A (0.74) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL30208389 | 0.79 | HIF1A (0.74) | CA12CA2CA9HIF1ACA1 | |
| SCHEMBL25167180 | 0.77 | CA2 (1.00) | CA12CA2CA9HIF1ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800590-B2 | CHEMICAL HERBICIDES IN AGRICULTURE | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY (CN) | 2004-10-05 | — | — | US | disclosed |
| US-20030220198-A1 | 2-pyrimidinyloxy-n-aryl-benzylamine derivatives,their processes and uses | ZHEIJIANG CHEMICAL INDUSTRY RESEARCH INSTITUTE (CN) | 2003-11-27 | — | — | US | disclosed |
| EP-1327629-A1 | NEW 2-PYRIMIDINYLOXY-N-ARYL-BENZYLAMINE DERIVATIVES, THEIR PROCESSES AND USES | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2003-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220198-A1 | 2-pyrimidinyloxy-n-aryl-benzylamine derivatives,their processes and uses | CBR3, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CA12 2646/4885CA2 60/4885CA9 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.