Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 14/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783001 | 0.87 | CA12 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6777661 | 0.87 | ALDH1A1 (0.51) | CA12CA1CA2CA9PPARG | |
| SCHEMBL6773797 | 0.86 | KMT2A (0.43) | ALDH1A1LMNACYP2C9TDP1 | |
| SCHEMBL6776784 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNATSHR | |
| SCHEMBL6781809 | 0.82 | POLB (0.42) | ALDH1A1CYP2C9TDP1 | |
| SCHEMBL6773576 | 0.82 | CA12 (0.43) | CA12CA1CA2CA9PPARG | |
| SCHEMBL6774657 | 0.81 | MAPT (0.49) | ALDH1A1LMNACYP2C9 | |
| SCHEMBL6777836 | 0.81 | TLR7 (0.43) | PPARGFBP1ALDH1A1LMNAALB | |
| SCHEMBL4793106 | 0.81 | FBP1 (0.45) | CA12CA1CA2CA9PPARG | |
| SCHEMBL6778251 | 0.80 | MEN1 (0.43) | ALDH1A1LMNACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |