Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780316 | 0.93 | TLR7 (0.38) | TGFBR1TLR7TLR8NUDT1LMNA | |
| SCHEMBL6281876 | 0.88 | TLR7 (0.38) | TLR7TLR8NUDT1LMNA | |
| SCHEMBL6284763 | 0.86 | ALDH1A1 (0.39) | TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6780878 | 0.86 | TLR7 (0.36) | TGFBR1TLR7TLR8NUDT1 | |
| SCHEMBL6783346 | 0.85 | TLR7 (0.38) | TGFBR1TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6773193 | 0.83 | GNAI3 (0.39) | TLR7TLR8NUDT1CTSDBACE1 | |
| SCHEMBL6776588 | 0.81 | EPHX2 (0.37) | TLR7TLR8NUDT1CTSDBACE1 | |
| SCHEMBL6780086 | 0.81 | TLR7 (0.41) | TGFBR1TLR7TLR8NUDT1ALDH1A1 | |
| SCHEMBL6779825 | 0.81 | MEN1 (0.40) | TGFBR1TLR7TLR8KDM4EALDH1A1 | |
| SCHEMBL5339393 | 0.80 | TLR8 (0.40) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |