Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287410 | 0.95 | ALDH1A1 (0.50) | RAB9AALOX12ALDH1A1KMT2AMEN1 | |
| SCHEMBL6782569 | 0.86 | SMN1; SMN2 (0.44) | RAB9AALOX12ALDH1A1KMT2AMEN1 | |
| SCHEMBL6286172 | 0.82 | ALDH1A1 (0.45) | RAB9AALOX12ALDH1A1KMT2ANPC1 | |
| SCHEMBL6779590 | 0.77 | MAPKAPK2 (0.43) | RAB9AALOX12ALDH1A1KMT2AMEN1 | |
| SCHEMBL6773093 | 0.77 | KMT2A (0.51) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL6774657 | 0.77 | MAPT (0.49) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL6670803 | 0.76 | TP53 (0.34) | ALDH1A1LMNAGAAL3MBTL1THRB | |
| SCHEMBL6778680 | 0.76 | HPGD (0.43) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6781809 | 0.76 | POLB (0.42) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL6110335 | 0.75 | KDM4E (0.39) | ALDH1A1GAAHPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |