Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369385 | 0.88 | PIN1 (0.47) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL28360178 | 0.86 | POLB (0.47) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL27540519 | 0.86 | PIN1 (0.49) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL6561186 | 0.84 | PIN1 (0.47) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL6562845 | 0.84 | PIN1 (0.47) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL1068997 | 0.81 | KMT2A (0.50) | TSHRKMT2AALDH1A1CYP2C19HIF1A | |
| SCHEMBL15991494 | 0.81 | EDNRB (0.46) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL28101975 | 0.81 | EDNRB (0.46) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL9475024 | 0.79 | SMN1; SMN2 (0.46) | PIN1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL6544643 | 0.79 | MAPT (0.47) | KMT2AALDH1A1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686369-B1 | α-hydrdroxylic acid derivatives, their production and use | ABBOTT GMBH & CO., KG (DE) | 2004-02-03 | — | — | US | disclosed |
| CN-1222146-A | Novel alpha-hydroxy acid derivatives, their preparation and their use | BASF AG (DE) | 1999-07-07 | — | — | CN | disclosed |