Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778376 | 0.92 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL6773247 | 0.87 | DRD2 (0.40) | EPHX2ALDH1A1TLR7TLR8 | |
| SCHEMBL6777534 | 0.81 | TLR7 (0.36) | ALDH1A1TLR7TLR8 | |
| SCHEMBL6774169 | 0.81 | TLR7 (0.39) | ALDH1A1TLR7TLR8 | |
| SCHEMBL6778839 | 0.80 | MAPKAPK2 (0.43) | TLR7TLR8 | |
| SCHEMBL6778983 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6777954 | 0.79 | TLR7 (0.41) | ALDH1A1TLR7TLR8KMT2A | |
| SCHEMBL6772297 | 0.79 | TLR7 (0.44) | ALDH1A1ACHETLR7TLR8MEN1 | |
| SCHEMBL6285998 | 0.79 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6782830 | 0.78 | HPGD (0.54) | ALDH1A1ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |