Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 14/20 | 0.47 |
| ▸ | CA2 | P00918 | 14/20 | 0.47 |
| ▸ | CA12 | O43570 | 7/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778839 | 0.89 | MAPKAPK2 (0.43) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL6773238 | 0.89 | QPCT (0.46) | HPGDSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6779814 | 0.81 | FAAH (0.47) | KMT2AHTTLMNAALDH1A1MAPT | |
| SCHEMBL6778425 | 0.80 | TLR7 (0.43) | — | |
| SCHEMBL6777534 | 0.80 | TLR7 (0.36) | HTTLMNAALDH1A1MAPT | |
| SCHEMBL6773645 | 0.80 | HDAC3 (0.44) | LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL6777851 | 0.80 | ALDH1A1 (0.46) | HPGDCA1CA2CA12CA9 | |
| SCHEMBL6772297 | 0.80 | TLR7 (0.44) | SMN1; SMN2MEN1KMT2AACHEALDH1A1 | |
| SCHEMBL6774751 | 0.79 | TLR7 (0.43) | SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL6285401 | 0.79 | TLR7 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |