Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778839 | 0.83 | MAPKAPK2 (0.43) | TLR7TLR8NUDT1LMNAMAPT | |
| SCHEMBL6778983 | 0.83 | SMN1; SMN2 (0.40) | NPC1ALDH1A1RECQLKDM4EHTT | |
| SCHEMBL6778424 | 0.83 | TLR7 (0.37) | TLR7TLR8NUDT1NPC1RAB9A | |
| SCHEMBL6285998 | 0.82 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6773238 | 0.81 | QPCT (0.46) | ALDH1A1LMNAMAPT | |
| SCHEMBL6777954 | 0.81 | TLR7 (0.41) | TLR7TLR8NUDT1ALDH1A1RECQL | |
| SCHEMBL6779304 | 0.81 | EPHX2 (0.42) | TLR7TLR8ALDH1A1 | |
| SCHEMBL6772297 | 0.81 | TLR7 (0.44) | TLR7TLR8NUDT1RAB9AALDH1A1 | |
| SCHEMBL6782830 | 0.80 | HPGD (0.54) | ALDH1A1HTTLMNAMAPT | |
| SCHEMBL6778763 | 0.79 | ALDH1A1 (0.42) | TLR7TLR8NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |