Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779679 | 0.94 | HPGD (0.46) | ALDH1A1TSHRHPGDALOX15HSD17B10 | |
| SCHEMBL6779320 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDALOX15HSD17B10 | |
| SCHEMBL6774292 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL6773389 | 0.81 | HPGD (0.43) | ALDH1A1TSHRHPGDALOX15HSD17B10 | |
| SCHEMBL6772471 | 0.79 | HPGD (0.46) | HPGDKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL6094589 | 0.78 | DYRK1A (0.37) | KDM4E | |
| SCHEMBL6773093 | 0.78 | KMT2A (0.51) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL6773502 | 0.78 | TLR7 (0.37) | SMN1; SMN2KMT2A | |
| SCHEMBL6780266 | 0.77 | CYP2C9 (0.44) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL6772950 | 0.77 | FAAH (0.53) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |