Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772194 | 0.91 | TLR7 (0.42) | TLR7TLR8NAMPTHDAC3 | |
| SCHEMBL6768616 | 0.89 | MCHR1 (0.47) | MCHR1TLR7TLR8GAANAMPT | |
| SCHEMBL6782531 | 0.88 | CCR3 (0.42) | ADORA2ATLR7TLR8 | |
| SCHEMBL6775141 | 0.88 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL6772917 | 0.86 | TLR7 (0.45) | TLR7TLR8NAMPTHDAC3 | |
| SCHEMBL6768596 | 0.86 | MCHR1 (0.47) | MCHR1ADORA2ATLR7TLR8GAA | |
| SCHEMBL6779049 | 0.86 | DRD2 (0.45) | TLR7TLR8HDAC3 | |
| SCHEMBL6779938 | 0.84 | TLR7 (0.41) | TLR7TLR8 | |
| SCHEMBL6768640 | 0.83 | TLR7 (0.43) | TLR7TLR8GAAHDAC3 | |
| SCHEMBL6778794 | 0.82 | SMN1; SMN2 (0.48) | TLR7TLR8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |