Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BRD1 | O95696 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780023 | 0.91 | TLR7 (0.42) | TLR7TLR8MAPTBRPF1S1PR1 | |
| SCHEMBL6773764 | 0.88 | TLR7 (0.38) | TLR7TLR8ALDH1A1POLB | |
| SCHEMBL6779938 | 0.85 | TLR7 (0.41) | TLR7TLR8RXFP1SCN9AGLO1 | |
| SCHEMBL6784556 | 0.84 | TLR7 (0.40) | TLR7TLR8MAPTKDM4EALDH1A1 | |
| SCHEMBL6780382 | 0.84 | TLR7 (0.44) | TLR7TLR8RXFP1SCN9AGLO1 | |
| SCHEMBL6780506 | 0.83 | ALDH1A1 (0.46) | TLR7ALDH1A1USP2POLBPKM | |
| SCHEMBL6774083 | 0.82 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6779139 | 0.82 | TLR7 (0.44) | TLR7TLR8ALDH1A1HPGD | |
| SCHEMBL6779376 | 0.82 | HTR7 (0.38) | TLR7MAPTS1PR1ALDH1A1POLB | |
| SCHEMBL6779163 | 0.82 | SCN1A (0.44) | TLR7TLR8KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |