Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778238 | 0.90 | TLR7 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL6783636 | 0.88 | TLR7 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6783392 | 0.88 | TLR7 (0.47) | TLR7TLR8KDM4ENUDT1 | |
| SCHEMBL6779845 | 0.87 | KDM4E (0.38) | TLR7KDM4ESCN9AGLO1SLC40A1 | |
| SCHEMBL6779938 | 0.86 | TLR7 (0.41) | TLR7TLR8KDM4EAPLNRSCN9A | |
| SCHEMBL6775218 | 0.85 | POLB (0.42) | TLR7TLR8 | |
| SCHEMBL6778739 | 0.84 | TLR7 (0.40) | TLR7TLR8KDM4EAPLNRSCN9A | |
| SCHEMBL6776957 | 0.83 | TLR7 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL6768596 | 0.83 | MCHR1 (0.47) | TLR7TLR8 | |
| SCHEMBL6780460 | 0.83 | TLR7 (0.44) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |