Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767206 | 0.83 | LMNA (0.51) | KDM1AHDAC1ERCC1ERCC4ROCK2 | |
| SCHEMBL5764848 | 0.77 | LMNA (0.57) | HDAC1EGFRRPS6KB1MAPK1CLK4 | |
| SCHEMBL5822709 | 0.74 | MAPK3 (0.53) | HDAC1PPARGERCC1ERCC4SYK | |
| SCHEMBL2924662 | 0.73 | HDAC6 (0.74) | HDAC1SYKROCK2ROCK1EGFR | |
| SCHEMBL1680963 | 0.73 | HDAC6 (0.58) | ADORA3ADORA2AADORA2BADORA1HDAC1 | |
| SCHEMBL5780921 | 0.72 | CCNC (0.46) | MAPT | |
| SCHEMBL3422647 | 0.72 | ROCK2 (0.62) | HDAC1PPARGERCC1ERCC4SYK | |
| SCHEMBL5823771 | 0.72 | SMN1; SMN2 (0.48) | ADORA3ADORA2AADORA2BADORA1KDM1A | |
| SCHEMBL10483392 | 0.71 | LOXL2 (0.58) | EGFRMAPK1 | |
| SCHEMBL30746358 | 0.71 | LOXL2 (0.58) | EGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004318111-A | COLORED PHOTOSENSITIVE RESIN COMPOSITION | SUMITOMO CHEM CO LTD | 2004-11-11 | — | — | JP | disclosed |
| US-20040204409-A1 | Bicyclic compounds as NR2B receptor antagonists | ANDO KAZUO (JP) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204409-A1 | Bicyclic compounds as NR2B receptor antagonists | GRIN1, GRIN2B, GRIN2A | TRPV1 65/4885ADORA3 412/4885ADORA2A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.